Press / Newsroom

Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are needed inside the body’s cells. The Fraunhofer Institute for Production Systems and Design Technology IPK and FDX Fluid Dynamix GmbH have worked together to develop a technology platform for the production of nanoparticles that can achieve particle quality and stability at levels previously out of reach: FDmiX, short for Fraunhofer Dynamic Mixing Technologies. Swiss chemical and pharmaceutical company Lonza has now licensed the technology for its own good manufacturing practice (GMP) production activities.

Many new drug candidates end up failing because they cause serious side effects in clinical trials even though lab tests involving cell cultures have been successful. This is a common occurrence if the cells used come from animal tissue, for example. Specially prepared cell cultures made from human tissue known as human induced pluripotent stem (hiPS) cells enable greater reliability in testing, thereby also increasing the chances that a drug will be approved. Fraunhofer researchers have developed innovative solutions for optimized production of cells in bioreactors and unique cryotechnologies. This is paving the way for efficient real-world use of these cell cultures in toxicity testing and drug discovery.

For some years now, the trend in the cosmetics and skincare sector has been toward transparency and natural, sustainable ingredients. A growing number of consumers are rejecting cosmetics that contain petroleum-derived mineral oils and silicone oils. As a result, manufacturers are increasingly turning toward plant-based oils, fats, and waxes as substitutes. Working in tandem with Kneipp GmbH, a well-known producer of cosmetic products and other items, the Fraunhofer Translational Center for Regenerative Therapies TLC-RT at the Fraunhofer Institute for Silicate Research ISC is conducting the first-ever systematic tests of the general protective and regenerative effects of plant oils on the skin. The researchers are using a 3D skin model cultured in vitro for their work.

Oxygen saturation in the blood that is either too low or too high can cause lasting physical harm or even death. This is why patients’ oxygen concentrations are monitored continuously in both intensive care and trauma units. However, the pulse oximeters typically clipped onto a patient’s fingertip for this purpose can be unreliable. Researchers at the Fraunhofer Institute for Physical Measurement Techniques IPM have developed a fluorescence-based sensor that measures the oxygen content of people’s breath directly and in real time in an effort to provide accurate figures in the future. The sensor determines the O2 concentration in the respiratory gas according to the principle of fluorescence quenching, which allows conclusions to be drawn about the oxygen saturation in the blood.

Parkinson’s disease is one of the most prevalent neurodegenerative conditions worldwide. It causes motor impairments such as tremors, slow movement, muscle stiffness, and balance problems. Memory can also worsen as the disease progresses. The individual course of the disease cannot be predicted, so experts recommend regular, close patient monitoring to allow for rapid responses to any changes in symptoms. New technological tools aim to facilitate communication between doctors, caregivers, and patients and improve the care situation. In the ParkProReakt project, researchers from the Fraunhofer Institute for Applied Information Technology FIT are working with partners to create a digital platform and app that, used with wearables, will track the course of the disease in an effort to improve quality of life for Parkinson’s patients.

Wood, we come into close contact with it daily. Children play around on wood floors, and wood furniture plays an important role in our work and sleep habits as well. To keep this natural material from aging prematurely, it’s important to protect it effectively against ultraviolet (UV) radiation. At the same time, people want to retain the look and feel of natural wooden surfaces, but the transparent protective coatings that are currently widely commercially available often contain harmful chemical compounds. To avoid using these substances, the Fraunhofer Institute for Process Engineering and Packaging IVV and Naturhaus Naturfarben GmbH are working together to develop a formula that provides harmless, transparent and 100 percent organic UV protection for wood.

Working together to expedite technological innovations in the fields of battery cell and semiconductor technology: That is the aim of a comprehensive international collaboration program funded by the Korean Ministry of Trade, Industry and Energy (MOTIE). The Fraunhofer-Gesellschaft, with eight of its institutes, is their partner in Germany. On Wednesday, the collaboration was sealed with a letter of agreement and the opening of a coordination hub.

In an effort to further develop the portfolio of the Fraunhofer-Gesellschaft in both subject-specific and commercial terms and ensure the research organization’s future viability, the executive board has adopted a package of measures involving the partial closure of the Fraunhofer Center for International Management and Knowledge Economy IMW and the elimination of the center’s independence. The remaining departments are to be integrated into the Fraunhofer Institute for Systems and Innovation Research ISI. In addition, the Fraunhofer Institute for Technological Trend Analysis INT is to be integrated into the Fraunhofer Institute for Communication, Information Processing and Ergonomics FKIE. These decisions are subject to the approval of the senate of the Fraunhofer-Gesellschaft.

Outer space has never before seemed so close, with spaceflight hovering within reach. To enhance the competitiveness of European space transportation systems, researchers at the Fraunhofer Institute for Laser Technology ILT are developing innovative manufacturing technologies for rocket components in the ENLIGHTEN project. The researchers will be presenting their results at the Hannover Messe (Hall 2, Booth B24) from April 22 to 26, 2024.

There is a high demand for AI solutions in industrial applications. These solutions need to be efficient, trustworthy and secure in order to be used in series production or quality control, for example. However, the new possibilities opened up by generative AI also raise questions. Can users rely on what a chatbot says? How can vulnerabilities in an AI model be detected early on during development? At the Hannover Messe 2024, the Fraunhofer Institute for Intelligent Analysis and Information Systems IAIS and the institutes of the Fraunhofer Big Data and Artificial Intelligence Alliance will be presenting two exhibits and several use cases centering on trustworthy AI solutions.