A new issue began to emerge at the turn of the year 2019/2020. It has since taken center stage in the public discourse and in the personal experience of individuals. The novel virus that the World Health Organization calls “severe acute respiratory syndrome coronavirus 2” has upended every aspect of public life. The WHO declared the outbreak of this virus to be “a public health emergency of international concern.” The COVID-19 pandemic is taking a toll on day-to-day life, on people’s health, on businesses, on the domestic economy and on global trade. The current situation and the dynamic developments throughout Germany and across the world are posing major challenges for people. Working at the forefront of the fight against the pandemic, Fraunhofer experts are supporting the efforts of industry and society to cope with the immediate effects and the consequences to come. Critical life sciences projects, our close collaboration with businesses, joint challenges with partners, direct and indirect medical support – we are reporting on all this and more in our special feature on the “Fraunhofer vs. Corona” campaign.